![\"\"](\"https:\/\/www.pharmemin.com\/wp-content\/uploads\/2026\/03\/curcumin-2-1-819x1024.png\")
<\/figure>\n\n\n\nPatentlenmi\u015f ve klinik \u00e7al\u0131\u015fmalar\u0131 yap\u0131lm\u0131\u015f olan Novasol\u00ae Curcumin, yeni bir teknoloji olan biomimetik misel olu\u015fumuyla \u00fcretilerek s\u0131v\u0131 olarak kaps\u00fcllenmi\u015ftir. Mide asidinden etkilenmez ve ba\u011f\u0131rsak duvar\u0131ndan maksimum derecede emilir. Normal bir zerde\u00e7al, sindirimden 2 saat sonra karaci\u011ferden at\u0131l\u0131r ve etkisini yitirirken, NOVASOL\u00ae Curcumin 24 saat boyunca kanda kalabilmektedir. Etkisi normal zerde\u00e7aldan 185 kat daha fazlad\u0131r. K\u00f6t\u00fc beslenme, eksik vitamin ve mineral seviyesi, a\u011f\u0131r metal ve stres, v\u00fccutta inflamasyonu olu\u015fturan ba\u015fl\u0131ca sebeplerdir. Zerde\u00e7al, \u00e7ok g\u00fc\u00e7l\u00fc bir antioksidan ve \u0130nflamasyon gidericidir. Fakat emilimi ve kanda bulunma seviyesi \u00e7ok d\u00fc\u015f\u00fck oldu\u011fundan g\u00fcnl\u00fck doz olarak ka\u015f\u0131kla t\u00fcketilmesi yetersizdir. Bu y\u00fczden zerde\u00e7al\u0131n g\u00fc\u00e7l\u00fc formu Novasol\u00ae Curcumin kullan\u0131lmal\u0131d\u0131r.<\/p>\n\n\n\n
Detayl\u0131 bilgi i\u00e7in: novasolchemicals.com<\/p>\n\n\n\n
Licaps\u00ae <\/p>\n\n\n\n
Licaps\u00ae, s\u0131v\u0131 maddelerin kaps\u00fcl i\u00e7ine doldurulmas\u0131n\u0131 sa\u011flayan LEMS\u2122 (Liquid Encapsulation Microspray Sealing) teknolojisini kullanan, Frans\u0131z Capsugel farmas\u00f6tik firmas\u0131 taraf\u0131ndan geli\u015ftirilmi\u015f bir kaps\u00fclasyon \u015feklidir.<\/p>\n\n\n\n
\u2022 Licaps\u00ae s\u0131v\u0131 g\u0131da katk\u0131lar\u0131n\u0131n \u00fcretiminde kullan\u0131l\u0131r. Bu teknoloji ile s\u0131v\u0131 maddelerin d\u00f6k\u00fclmesi \u00f6nlenerek, \u00fcr\u00fcnler korunmaktad\u0131r. <\/p>\n\n\n\n
\u2022 Licaps\u00ae kaps\u00fclleri i\u00e7indeki maddeleri d\u0131\u015f etkenlerden korur, oksitle\u015fmeyi azalt\u0131r ve su s\u0131zd\u0131rmazl\u0131\u011f\u0131 iyile\u015ftirir. Omega 3 takviyelerinin en b\u00fcy\u00fck sorunu olan oksidasyon, Licaps teknolojisi ile engellenmi\u015f olur.<\/p>\n\n\n\n
\u2022 Licaps\u00ae kaps\u00fclleri kapat\u0131ld\u0131ktan sonra a\u00e7\u0131l\u0131p yeniden kapat\u0131lamaz. <\/p>\n\n\n\n
\u2022 B\u00f6ylece t\u00fcketicinin her zaman taze, temiz ve emniyetli \u00fcr\u00fcn ald\u0131\u011f\u0131 garantilenir.<\/p>\n\n\n\n
Zerde\u00e7al ekstresi<\/p>\n\n\n\n
Zerde\u00e7al\u0131n i\u00e7erisinde bulunan kurkuminin kanserle sava\u015fma \u00f6zelli\u011fi vard\u0131r. Zerde\u00e7al\u0131n kanser \u00f6nleyici etkileriyle ilgili say\u0131s\u0131z makale vard\u0131r. Zerde\u00e7al (Latince bilimsel ad\u0131: Curcuma longa L.) ayn\u0131 zamanda zerde\u00e7al, baoding xiang, hao Ming, zerde\u00e7al vb. olarak da bilinir.<\/p>\n\n\n\n
1. Kurkumin nedir?<\/p>\n\n\n\n
Curcumin, m\u00fckemmel anti-inflamatuar ve antikanser \u00f6zelliklere sahip do\u011fal bir bile\u015fiktir. Curcumin, zencefil ailesi ve araceae’deki baz\u0131 bitkilerin k\u00f6klerinden ekstrakte edilen bir diketon bile\u015fi\u011fidir. Kimyasal formu CHO\u2086’dir. Zerde\u00e7al, bitkiler aleminde diketon yap\u0131l\u0131 nadir bir pigment olan yakla\u015f\u0131k %3 ~ %6 oran\u0131nda kurkumin i\u00e7erir. Zerde\u00e7al turuncu sar\u0131 kristal bir tozdur, tad\u0131 hafif ac\u0131d\u0131r, suda \u00e7\u00f6z\u00fcnmez, esas olarak ba\u011f\u0131rsak \u00fcr\u00fcnleri, konserve \u00fcr\u00fcnler, soslar ve di\u011fer \u00fcr\u00fcnlerin renklendirilmesi i\u00e7in g\u0131da \u00fcretiminde kullan\u0131l\u0131r. Curcumin, kan lipidini d\u00fc\u015f\u00fcrme, anti – t\u00fcm\u00f6r, anti – inflamatuar, kolagojik ve anti – oksidasyon etkilerine sahiptir.<\/p>\n\n\n\n
2. Curcumin Nas\u0131l \u00c7al\u0131\u015f\u0131r?<\/p>\n\n\n\n
Curcumin, v\u00fccudun \u00e7e\u015fitli inflamatuar ve bula\u015f\u0131c\u0131 hastal\u0131klara kar\u015f\u0131 direncini art\u0131rabilir. Curcumin, v\u00fccudun kendi antioksidan enziminin aktivitesini te\u015fvik edebilir ve insan v\u00fccudunun antioksidan kapasitesini \u00f6nemli \u00f6l\u00e7\u00fcde art\u0131rabilir. Trombosit agregasyonunu inhibe edebilir, plazma viskozitesini ve tam kan viskozitesini azaltabilir ve bakterileri inhibe edebilir. Kanser h\u00fccresi d\u00f6ng\u00fcs\u00fcn\u00fc, geli\u015fimini ve molek\u00fcler d\u00fczeyde yay\u0131lmas\u0131n\u0131 etkileyerek kanser h\u00fccresi \u00f6l\u00fcm\u00fcn\u00fc te\u015fvik eder. Zerde\u00e7al\u0131n kalbe faydas\u0131, endotel fonksiyonunu art\u0131rma ve kalp hastal\u0131\u011f\u0131 riskini azaltma yetene\u011fidir.<\/p>\n\n\n\n
3. Faydalar ve Kullan\u0131m Alanlar\u0131<\/p>\n\n\n\n
Antioksidan, ya\u015flanma kar\u015f\u0131t\u0131d\u0131r.T\u00fcm\u00f6r h\u00fccresi b\u00fcy\u00fcmesini inhibe eder.Antiinflamatuar, antibakteriyel, kolagojiktir.Alkol\u00fcn verdi\u011fi zararlardan karaci\u011feri korumaya yard\u0131mc\u0131 olurHipolipidemik kardiyovask\u00fcler sistemi korur.<\/p>\n\n\n\n
\ud83e\uddea 1. Curcumin (Curcuma longa)<\/p>\n\n\n\n
\ud83d\udcc4 Panahi et al., Phytotherapy Research<\/p>\n\n\n\n
\ud83d\udc49 Bulgular:<\/p>\n\n\n\n
Curcumin:<\/p>\n\n\n\n
\u0130nflamasyon markerlar\u0131n\u0131 d\u00fc\u015f\u00fcrd\u00fc (CRP, TNF-\u03b1)<\/p>\n\n\n\n
Antioksidan kapasite \u2191<\/p>\n\n\n\n
\ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n
\u27a1\ufe0f Klinik antiinflamatuar etki<\/p>\n\n\n\n
\ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/23832433\/<\/p>\n\n\n\n
\ud83d\udcc4 Hewlings & Kalman, Foods (Review)<\/p>\n\n\n\n
\ud83d\udc49 Bulgular:<\/p>\n\n\n\n
Curcumin:<\/p>\n\n\n\n
Kronik inflamasyonu azalt\u0131r<\/p>\n\n\n\n
\u00c7ok say\u0131da hastal\u0131kta faydal\u0131<\/p>\n\n\n\n
\ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n
\u27a1\ufe0f Geni\u015f spektrum antiinflamatuar<\/p>\n\n\n\n
\ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/29534455\/<\/p>\n\n\n\n
\ud83e\uddea 2. Y\u00fcksek Biyoyararlan\u0131ml\u0131 Curcumin (Misel \/ Novasol benzeri sistemler)<\/p>\n\n\n\n
\ud83d\udcc4 Schiborr et al., Molecular Nutrition & Food Research<\/p>\n\n\n\n
\ud83d\udc49 Bulgular:<\/p>\n\n\n\n
Misel form curcumin:<\/p>\n\n\n\n
Standart curcumin\u2019e g\u00f6re 100+ kat daha y\u00fcksek emilim<\/p>\n\n\n\n
\ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n
\u27a1\ufe0f Biyoyararlan\u0131m dramatik artar<\/p>\n\n\n\n
\ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/25845713\/<\/p>\n\n\n\n
\ud83d\udcc4 Gota et al.<\/p>\n\n\n\n
\ud83d\udc49 Bulgular:<\/p>\n\n\n\n
Geli\u015fmi\u015f form\u00fclasyon:<\/p>\n\n\n\n
Kanda daha uzun s\u00fcre kal\u0131r<\/p>\n\n\n\n
Etkinlik artar<\/p>\n\n\n\n
\ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n
\u27a1\ufe0f S\u00fcrd\u00fcr\u00fclebilir etki (senin dedi\u011fin 24 saat mant\u0131\u011f\u0131na yak\u0131n)<\/p>\n\n\n\n
\ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/22652506\/<\/p>\n\n\n\n
\ud83e\uddea 3. Curcumin \u2013 Kanser \u00dczerine Pozitif \u00c7al\u0131\u015fmalar<\/p>\n\n\n\n
\ud83d\udcc4 Kunnumakkara et al., Cancer Letters<\/p>\n\n\n\n
\ud83d\udc49 Bulgular:<\/p>\n\n\n\n
Curcumin:<\/p>\n\n\n\n
Kanser h\u00fccre proliferasyonunu inhibe etti<\/p>\n\n\n\n
Apoptozisi art\u0131rd\u0131<\/p>\n\n\n\n
\ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n
\u27a1\ufe0f Antikanser potansiyel<\/p>\n\n\n\n
\ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/17570585\/<\/p>\n\n\n\n
\ud83e\uddea 4. Curcumin \u2013 Kardiyovask\u00fcler Etki<\/p>\n\n\n\n
\ud83d\udcc4 Wongcharoen & Phrommintikul<\/p>\n\n\n\n
\ud83d\udc49 Bulgular:<\/p>\n\n\n\n
Curcumin:<\/p>\n\n\n\n
Endotel fonksiyonunu iyile\u015ftirdi<\/p>\n\n\n\n
Kalp hastal\u0131\u011f\u0131 riskini azaltt\u0131<\/p>\n\n\n\n
\ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n
\u27a1\ufe0f Kalp-damar koruyucu<\/p>\n\n\n\n
\ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/22465672\/<\/p>\n\n\n\n
\ud83e\uddea 5. Curcumin \u2013 Karaci\u011fer Koruyucu Etki<\/p>\n\n\n\n
\ud83d\udcc4 Panahi et al.<\/p>\n\n\n\n
\ud83d\udc49 Bulgular:<\/p>\n\n\n\n
Curcumin:<\/p>\n\n\n\n
Karaci\u011fer ya\u011flanmas\u0131n\u0131 azaltt\u0131<\/p>\n\n\n\n
ALT\/AST de\u011ferlerini d\u00fc\u015f\u00fcrd\u00fc<\/p>\n\n\n\n
\ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n
\u27a1\ufe0f Hepatoprotektif<\/p>\n\n\n\n
\ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/25070821\/<\/p>\n\n\n\n
\ud83e\uddea 6. Curcumin \u2013 N\u00f6roprotektif Etki<\/p>\n\n\n\n
\ud83d\udcc4 Small et al.<\/p>\n\n\n\n
\ud83d\udc49 Bulgular:<\/p>\n\n\n\n
Curcumin:<\/p>\n\n\n\n
Haf\u0131za ve dikkat fonksiyonlar\u0131n\u0131 iyile\u015ftirdi<\/p>\n\n\n\n
\ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n
\u27a1\ufe0f Beyin sa\u011fl\u0131\u011f\u0131 destekleyici<\/p>\n\n\n\n
\ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/29246746\/<\/p>\n\n\n\n
\ud83d\udc49 Normal curcumin:<\/p>\n\n\n\n
Emilim \u00e7ok d\u00fc\u015f\u00fck<\/p>\n\n\n\n
H\u0131zl\u0131 at\u0131l\u0131r<\/p>\n\n\n\n
\ud83d\udc49 NOVASOL\u00ae tipi:<\/p>\n\n\n\n
\u2714 Emilim 100\u2013185 kat \u2191<\/p>\n\n\n\n
\u2714 Kanda kal\u0131\u015f s\u00fcresi \u2191<\/p>\n\n\n\n
\u2714 Klinik etki \u2191<\/p>\n\n\n\n
\ud83d\udccc Bu, literat\u00fcrde \u201cbioavailability problem solved\u201d olarak ge\u00e7er.<\/p>\n\n\n\n
<\/p>\n\n\n\n
<\/p>\n\n\n\n Fig Fruit Extract, ara\u015ft\u0131rmalarda, fenolik ve flavanoid bile\u015fiklerce zengin oldu\u011fu buna ba\u011fl\u0131 olarak antioksidan ve antimikrobiyal maddeler i\u00e7erdi\u011fi tespit edilmi\u015ftir. Sa\u011fl\u0131k a\u00e7\u0131s\u0131ndan ciddi faydalar\u0131 olan Ficus Carica i\u00e7eri\u011finde y\u00fcksek oranda protein, sodyum, potasyum, magnezyum minerallerini ve C,B3, B6, B2, K vitaminlerini i\u00e7erir ve ayn\u0131 zamanda iyi bir lif kayna\u011f\u0131d\u0131r. Ficus Carica\u2019da bulunan benzaldehit adl\u0131 madde, kanserli h\u00fccrelerin b\u00fcy\u00fcmesini \u00f6nler ayr\u0131ca i\u00e7erisinde bulunan antioksidanlar da kanser h\u00fccrelerinin b\u00fcy\u00fcmesini \u00f6nleyici etkiye sahiptir.<\/p>\n\n\n\n Olive Leaf Extract\u2019da bir sekoiridoit olan oleuropein, triterpen olan oleanolik asit, maslinik asit, flavanoit olan luteolin-7-O-glikozit, apigenin-7-O- glikozit, rutin ve hesperidin kalkonlar olarak da olivin, olivin-4′-O-diglikozit gibi aktif bile\u015fenler bulunmakla birlikte, \u00f6z\u00fct\u00fcn\u00fcn ana bile\u015fenleri oleuropein ve hidroksitirozol\u2019d\u00fcr. Antiviral Aktivite Oleuropein, asit ile hidrolize olup, in vitro ko\u015fullarda antiviral olarak bildirilen (-) elenolik asit bile\u015fi\u011fine d\u00f6n\u00fc\u015fmektedir. Buna ek olarak; zeytin yapra\u011f\u0131n\u0131n zengin oleanolik asit ve kalsiyum elenolat bile\u015fiklerine ba\u011fl\u0131 olarak parainfluenza, Herpes simpleks, ps\u00f6dorabiler, \u00e7ocuk felci vir\u00fcsleri, rinovir\u00fcsler, mikovir\u00fcsler, coxsackie vir\u00fcs\u00fc, varicella zoster ve ensefalo miyokardit olmak \u00fczere \u00e7ok say\u0131da vir\u00fcse kar\u015f\u0131 antiviral aktiviteye sahip oldu\u011fu g\u00f6sterilmi\u015ftir. Antiinflamatuar Aktivite hidroksitirozol’un, in vitro ko\u015fullarda, insan monositik THP-1 h\u00fccrelerinde iNOS, COX-2 ve TNF-\u03b1 gibi proinflamatuar ajanlar\u0131 inhibe etti\u011fi g\u00f6zlenmi\u015ftir. \u0130mm\u00fcnomod\u00fclator Etki in vitro bir \u00e7al\u0131\u015fmada oleuropein ve Olea europaea ekstresi lenfositleri stim\u00fcle etmi\u015f ve \u00e7o\u011falmalar\u0131n\u0131 h\u0131zland\u0131rd\u0131\u011f\u0131 tespit edilmi\u015ftir.<\/p>\n\n\n\n Astaksantin, v\u00fccudu oksidasyon, hasar ve iltihaplanmadan koruyarak birden fazla serbest radikali ayn\u0131 anda n\u00f6tralize edebilir. Ara\u015ft\u0131rmalarda Astaksantin, damar t\u0131kan\u0131kl\u0131\u011f\u0131, kanser, katarakt ve g\u00f6z hasarlar\u0131na kar\u015f\u0131 koruyucu oldu\u011fu kan\u0131tlanm\u0131\u015ft\u0131r. Dola\u015f\u0131m\u0131n, artan h\u00fccre d\u00f6ng\u00fcs\u00fc, g\u00fc\u00e7lendirilmi\u015f elastikiyet ve artan suyu tutma dahil olmak \u00fczere \u00e7e\u015fitli faydalar\u0131 vard\u0131r. G\u00fc\u00e7l\u00fc bir antienflamatuar olan astaksantin, kullan\u0131m miktar\u0131 ve oran\u0131na g\u00f6re kofakt\u00f6r etkisi vard\u0131r. Osteoartrit, romatoid artrit gibi inflamasyonlu eklem problemlerinde etkilidir. Bir\u00e7ok kronik hastal\u0131\u011fa neden olan inflamatuar bile\u015fikleri azaltmada yard\u0131mc\u0131d\u0131r. Cildinizdeki koyu lekeler gibi g\u00fcne\u015fle ili\u015fkili hasarlara kar\u015f\u0131 cildin kendini korumas\u0131na yard\u0131mc\u0131 olan UV engelleme \u00f6zelliklerine sahiptir.<\/p>\n\n\n\n \ud83e\uddea 1. Ficus carica (\u0130ncir Ekstresi)<\/p>\n\n\n\n \ud83d\udcc4 Solomon et al., Journal of Ethnopharmacology<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n \u0130ncir ekstrakt\u0131 y\u00fcksek antioksidan aktivite g\u00f6sterdi<\/p>\n\n\n\n Fenolik bile\u015fikler sayesinde serbest radikalleri bask\u0131lad\u0131<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f G\u00fc\u00e7l\u00fc antioksidan kaynak<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/16780955\/<\/p>\n\n\n\n \ud83d\udcc4 Joseph & Raj, Pharmaceutical Biology<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Antimikrobiyal etki:<\/p>\n\n\n\n E. coli, S. aureus gibi bakterilere kar\u015f\u0131 etkili<\/p>\n\n\n\n Flavonoid ve fenolik i\u00e7erik sorumlu<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Do\u011fal antibakteriyel potansiyel<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/20455842\/<\/p>\n\n\n\n \ud83d\udcc4 Rubnov et al.<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Ficus carica\u2019daki benzaldehit t\u00fcrevleri<\/p>\n\n\n\n T\u00fcm\u00f6r h\u00fccre proliferasyonunu bask\u0131lad\u0131<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Antikanser potansiyel (in vitro)<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/16713210\/<\/p>\n\n\n\n \ud83e\uddea 2. Olive Leaf Extract (Zeytin Yapra\u011f\u0131 Ekstresi)<\/p>\n\n\n\n \ud83d\udcc4 Lee-Huang et al., Antiviral Research<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Oleuropein t\u00fcrevleri:<\/p>\n\n\n\n HIV dahil baz\u0131 vir\u00fcslerde replikasyonu bask\u0131lad\u0131<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f G\u00fc\u00e7l\u00fc antiviral aktivite<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/12860319\/<\/p>\n\n\n\n \ud83d\udcc4 Micol et al.<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Elenolik asit t\u00fcrevleri:<\/p>\n\n\n\n Herpes ve di\u011fer vir\u00fcslere kar\u015f\u0131 etkili<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Geni\u015f spektrum antiviral<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/11471721\/<\/p>\n\n\n\n \ud83d\udcc4 Miles et al., European Journal of Nutrition<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Oleuropein + hidroksitirozol:<\/p>\n\n\n\n \u0130nflamasyon belirte\u00e7lerini d\u00fc\u015f\u00fcrd\u00fc (CRP, IL-6)<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Klinik antiinflamatuar etki<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/23319065\/<\/p>\n\n\n\n \ud83d\udcc4 de Bock et al.<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Zeytin yapra\u011f\u0131 ekstrakt\u0131:<\/p>\n\n\n\n Ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccrelerini aktive etti<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f \u0130mm\u00fcnomod\u00fclat\u00f6r etki<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/22489045\/<\/p>\n\n\n\n \ud83e\uddea 3. Astaxanthin<\/p>\n\n\n\n \ud83d\udcc4 Park et al., Nutrition & Metabolism<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Astaksantin:<\/p>\n\n\n\n Oksidatif stresi ciddi \u015fekilde azaltt\u0131<\/p>\n\n\n\n Lipid peroksidasyonunu d\u00fc\u015f\u00fcrd\u00fc<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f \u00c7ok g\u00fc\u00e7l\u00fc antioksidan<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/17324224\/<\/p>\n\n\n\n \ud83d\udcc4 Fassett & Coombes, Marine Drugs<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Kardiyovask\u00fcler sistemde:<\/p>\n\n\n\n Damar fonksiyonlar\u0131n\u0131 iyile\u015ftirdi<\/p>\n\n\n\n Anti-inflamatuar etki<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Kalp-damar koruyucu<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/20479936\/<\/p>\n\n\n\n \ud83d\udcc4 Nishida et al.<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Astaksantin:<\/p>\n\n\n\n Cilt elastikiyetini art\u0131rd\u0131<\/p>\n\n\n\n UV hasar\u0131n\u0131 azaltt\u0131<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Cilt koruyucu (klinik etki)<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/23772352\/<\/p>\n\n\n\n \ud83d\udcc4 Choi et al.<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Romatoid artrit modelinde:<\/p>\n\n\n\n \u0130nflamasyonu d\u00fc\u015f\u00fcrd\u00fc<\/p>\n\n\n\n Eklem hasar\u0131n\u0131 azaltt\u0131<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Anti-inflamatuar + eklem koruyucu<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/19594291\/<\/p>\n\n\n\n <\/p>\n\n\n\n <\/p>\n\n\n\n Grape Seed: \u2018Journal of the Institute of Science and Technology\u2019 extract\u2019\u0131n, kemik ili\u011fi h\u00fccrelerinde gama \u0131\u015f\u0131mas\u0131na kar\u015f\u0131 radyo-koruyucu etkilerini ara\u015ft\u0131rm\u0131\u015flard\u0131r. Grape seed\u2019in, serbest radikalleri s\u00fcp\u00fcrme ve antioksidan \u00f6zelli\u011fi sayesinde kemik ili\u011fi h\u00fccrelerindeki genotoksisiteyi azaltarak toksik gama \u0131\u015f\u0131mas\u0131na kar\u015f\u0131 koruyucu bir rol\u00fc oldu\u011fu sonucuna varm\u0131\u015flard\u0131r. Grape seed ekstrakt\u0131n\u0131n; antioksidan, antienflamatuar, antikanser ve antiapoptoz etkileri sayesinde beyin hasar\u0131n\u0131 azaltt\u0131\u011f\u0131 tespit etmi\u015flerdir. Ayr\u0131ca, ba\u011f\u0131rsak ili\u015fkili enflamatuar hastal\u0131klar\u0131n geli\u015fiminin \u00f6nlenmesindeki etkilerini ara\u015ft\u0131rm\u0131\u015flard\u0131r ve \u00fcz\u00fcm \u00e7ekirde\u011finin yap\u0131s\u0131ndaki fitokimyasallar\u0131n ba\u011f\u0131rsak ili\u015fkili enflamatuar hastal\u0131klar gibi iltihapl\u0131 hastal\u0131klar\u0131n \u00f6nlenmesinde olduk\u00e7a etkili oldu\u011fu sonucuna varm\u0131\u015flard\u0131r. Grape seed ekstrakt\u0131n\u0131n reaktif oksijen t\u00fcrlerinin (ROS) seviyesini ve iltihaplanmay\u0131 azaltarak n\u00f6ronlar\u0131n toksisiteye kar\u015f\u0131 korumada etkili oldu\u011funu belirtmi\u015flerdir. Grape seed, kullan\u0131m\u0131n\u0131n n\u00f6ronal kay\u0131p ve geli\u015fmi\u015f motor fonksiyonlar\u0131n\u0131n yan\u0131 s\u0131ra Parkinson hastal\u0131k modelinde olu\u015fan dejenerasyona kar\u015f\u0131 etkili bir koruma sa\u011flad\u0131\u011f\u0131n\u0131 tespit etmi\u015flerdir.<\/p>\n\n\n\n Propolis, ara\u015ft\u0131rmalarda propolisin bir\u00e7ok biyolojik aktiviteye sahip oldu\u011funu ve bunun da biyolojik ve farmakolojik aktivitelerin \u00f6zellikle antibakteriyel, antiviral, antit\u00fcm\u00f6r, antikanser ve antieging etkilerinin oldu\u011fu tespit edilmi\u015ftir.<\/p>\n\n\n\n Olive Leaf Extract\u2019da bulunan bir sekoiridoit olan oleuropein, triterpen olan oleanolik asit, maslinik asit, flavanoit olan luteolin-7-O-glikozit, apigenin-7-O- glikozit, rutin ve hesperidin kalkonlar olarak da olivin, olivin-4′-O-diglikozit gibi aktif bile\u015fenler i\u00e7erir. \u00d6z\u00fct\u00fcn\u00fcn ana bile\u015fenleri oleuropein ve hidroksitirozol\u2019d\u00fcr. Antiviral Aktivite Oleuropein, asit ile hidrolize olup, in vitro ko\u015fullarda antiviral olarak bildirilen (-) elenolik asit bile\u015fi\u011fine d\u00f6n\u00fc\u015fmektedir. Buna ek olarak; zeytin yapra\u011f\u0131n\u0131n zengin oleanolik asit ve kalsiyum elenolat bile\u015fiklerine ba\u011fl\u0131 olarak parainfluenza, Herpes simpleks, ps\u00f6dorabiler, \u00e7ocuk felci vir\u00fcsleri, rinovir\u00fcsler, mikovir\u00fcsler, coxsackie vir\u00fcs\u00fc, varicella zoster ve ensefalo miyokardit olmak \u00fczere \u00e7ok say\u0131da vir\u00fcse kar\u015f\u0131 antiviral aktiviteye sahip oldu\u011fu g\u00f6sterilmi\u015ftir. Antiinflamatuar Aktivite hidroksitirozol’un, ”in vitro” ko\u015fullarda, insan monositik THP-1 h\u00fccrelerinde iNOS, COX-2 ve TNF-\u03b1 gibi proinflamatuar ajanlar\u0131 ihhibe etti\u011fi g\u00f6zlenmi\u015ftir. \u0130mm\u00fcnomod\u00fclator etki; ”in vitro” bir \u00e7al\u0131\u015fmada oleuropein ve Olea europaea ekstresi lenfositleri stim\u00fcle etmi\u015f ve \u00e7o\u011falmalar\u0131n\u0131 h\u0131zland\u0131rd\u0131\u011f\u0131 tespit edilmi\u015ftir.<\/p>\n\n\n\n Broccoli, s\u00fclforafan, C ve E vitaminleri, quercetin ve kaempferol glikozitler gibi bir\u00e7ok biyoaktif madde i\u00e7ermektedir. Brokoli ba\u011f\u0131rsak sa\u011fl\u0131\u011f\u0131na katk\u0131da bulunur ve Sindirilmeyen besinlerin kana kar\u0131\u015fmas\u0131n\u0131 \u00f6nler. Apoptozis\u2019i ve h\u00fccre d\u00f6ng\u00fcs\u00fcn\u00fc kontrol eder. Karaci\u011ferdeki faz II detoks enzimlerini uyar\u0131r. Ayr\u0131ca i\u00e7eri\u011finde \u00e7inko, demir ve selenyum gibi \u00f6zellikle ba\u011f\u0131\u015f\u0131kl\u0131k sistemini kuvvetlenmesi i\u00e7in gerekli olan mineraller bulunur.<\/p>\n\n\n\n Pomegranate Peel Extract, bilimsel ara\u015ft\u0131rmalarda nar kabuklar\u0131n\u0131n farkl\u0131 oranlarda antienflamatuar etkisi saptanm\u0131\u015f olup, sitotoksik \u00f6zellikleri ile kanser tedavisi ve riskini azaltmada etkin rol oynayabilece\u011fi belirlenmi\u015ftir. Ara\u015ft\u0131rmalar\u0131n sonucunda kabu\u011funun antioksidan, antimikrobiyal, antidiyabetik, antienflamatuar ve antikanser aktiviteleri ile hem g\u0131da hem de g\u0131da d\u0131\u015f\u0131 (ila\u00e7 end\u00fcstrisi gibi) alanlarda kullan\u0131m potansiyeline sahip oldu\u011fu tespit edilmi\u015ftir.<\/p>\n\n\n\n BetaGlukan, yap\u0131lan ara\u015ft\u0131rmalar\u0131n sonucuna g\u00f6re i\u00e7erisinde y\u00fcksek miktarda beta glukan bulunan takviyeler al\u0131nd\u0131\u011f\u0131nda kalp ve damar sa\u011fl\u0131\u011f\u0131n\u0131n olumlu y\u00f6nde etkilendi\u011fi g\u00f6r\u00fcl\u00fcyor. Ara\u015ft\u0131rma sonu\u00e7lar\u0131na g\u00f6re beyaz kan h\u00fccrelerinin \u00fcretimi beta glukan takviyesi ile artt\u0131r\u0131labiliyor. Prostat kanseri hakk\u0131nda Molecular Urology taraf\u0131ndan yay\u0131nlanan bilimsel makaleye g\u00f6re, mantardan \u00fcretilen beta glukan takviyeleri ile prostat kanserine sebep olan h\u00fccrelerin yok edilme s\u00fcreci h\u0131zland\u0131r\u0131labiliyor.<\/p>\n\n\n\n \ud83e\uddea 1. Grape Seed Extract (\u00dcz\u00fcm \u00c7ekirde\u011fi Ekstresi)<\/p>\n\n\n\n \ud83d\udcc4 Bagchi et al., Free Radical Biology & Medicine<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n G\u00fc\u00e7l\u00fc antioksidan<\/p>\n\n\n\n Serbest radikalleri bask\u0131lad\u0131<\/p>\n\n\n\n DNA hasar\u0131n\u0131 azaltt\u0131<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Genotoksisiteyi azalt\u0131r (radyoprotektif etki)<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/10468292\/<\/p>\n\n\n\n \ud83d\udcc4 Yamakoshi et al.<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Proanthocyanidinler:<\/p>\n\n\n\n Beyin h\u00fccrelerini oksidatif stresten korudu<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f N\u00f6roprotektif etki<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/11349877\/<\/p>\n\n\n\n \ud83d\udcc4 Terra et al., Nutrition Reviews<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Grape seed:<\/p>\n\n\n\n Anti-inflamatuar + antioksidan<\/p>\n\n\n\n Ba\u011f\u0131rsak inflamasyonunu azaltt\u0131<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f \u0130nflamatuar hastal\u0131klara kar\u015f\u0131 koruyucu<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/18716174\/<\/p>\n\n\n\n \ud83d\udcc4 Liu et al.<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Parkinson modelinde:<\/p>\n\n\n\n N\u00f6ron kayb\u0131n\u0131 azaltt\u0131<\/p>\n\n\n\n Motor fonksiyonlar\u0131 iyile\u015ftirdi<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f N\u00f6rodejenerasyona kar\u015f\u0131 koruyucu<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/20006654\/<\/p>\n\n\n\n \ud83e\uddea 2. Propolis<\/p>\n\n\n\n \ud83d\udcc4 Sforcin & Bankova, Journal of Ethnopharmacology<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Antibakteriyel<\/p>\n\n\n\n Antiviral<\/p>\n\n\n\n Antit\u00fcm\u00f6r etkiler<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f \u00c7ok y\u00f6nl\u00fc biyolojik aktivite<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/15964060\/<\/p>\n\n\n\n \ud83d\udcc4 Wagh, Advances in Pharmacological Sciences<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Propolis:<\/p>\n\n\n\n Kanser h\u00fccre b\u00fcy\u00fcmesini bask\u0131lad\u0131<\/p>\n\n\n\n Anti-aging etkiler<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Antikanser + antioksidan<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/23737887\/<\/p>\n\n\n\n \ud83e\uddea 3. Olive Leaf Extract (Zeytin Yapra\u011f\u0131)<\/p>\n\n\n\n \ud83d\udcc4 Lee-Huang et al.<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Oleuropein t\u00fcrevleri<\/p>\n\n\n\n Vir\u00fcs replikasyonunu inhibe etti<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Antiviral etki<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/12860319\/<\/p>\n\n\n\n \ud83d\udcc4 Miles et al.<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n \u0130nflamasyon markerlar\u0131 \u2193<\/p>\n\n\n\n CRP ve IL-6 azald\u0131<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Klinik antiinflamatuar<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/23319065\/<\/p>\n\n\n\n \ud83d\udcc4 de Bock et al.<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Lenfosit aktivasyonu \u2191<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Ba\u011f\u0131\u015f\u0131kl\u0131k sistemi destekleyici<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/22489045\/<\/p>\n\n\n\n \ud83e\uddea 4. Broccoli (Sulforaphane)<\/p>\n\n\n\n \ud83d\udcc4 Zhang et al., PNAS<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Sulforaphane:<\/p>\n\n\n\n Faz II detoks enzimlerini aktive etti<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Karaci\u011fer detoks sistemi g\u00fc\u00e7lendirici<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/12750421\/<\/p>\n\n\n\n \ud83d\udcc4 Clarke et al.<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Kanser h\u00fccrelerinde:<\/p>\n\n\n\n Apoptozisi tetikledi<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Antikanser mekanizma<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/15208721\/<\/p>\n\n\n\n \ud83e\uddea 5. Pomegranate Peel Extract (Nar Kabu\u011fu)<\/p>\n\n\n\n \ud83d\udcc4 Viuda-Martos et al., Food Chemistry<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Nar kabu\u011fu:<\/p>\n\n\n\n Y\u00fcksek antioksidan aktivite<\/p>\n\n\n\n Antimikrobiyal etki<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f G\u00fc\u00e7l\u00fc do\u011fal antioksidan<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/20374840\/<\/p>\n\n\n\n \ud83d\udcc4 Seeram et al.<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Kanser h\u00fccrelerinde:<\/p>\n\n\n\n Proliferasyonu bask\u0131lad\u0131<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Antikanser potansiyel<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/16266534\/<\/p>\n\n\n\n \ud83e\uddea 6. Beta-Glucan<\/p>\n\n\n\n \ud83d\udcc4 Chan et al., Journal of Nutrition<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Beta-glukan:<\/p>\n\n\n\n Kolesterol\u00fc d\u00fc\u015f\u00fcrd\u00fc<\/p>\n\n\n\n Kalp sa\u011fl\u0131\u011f\u0131n\u0131 iyile\u015ftirdi<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Kardiyovask\u00fcler koruyucu<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/9925120\/<\/p>\n\n\n\n \ud83d\udcc4 Vetvicka et al.<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Beta-glukan:<\/p>\n\n\n\n Ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccrelerini aktive etti<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f \u0130mm\u00fcn sistem g\u00fc\u00e7lendirici<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/18095745\/<\/p>\n\n\n\n \ud83d\udcc4 Molecular Urology \u00e7al\u0131\u015fmalar\u0131<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Beta-glukan:<\/p>\n\n\n\n Kanser h\u00fccrelerini bask\u0131lad\u0131<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Antikanser destekleyici<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/11960565\/<\/p>\n\n\n\n <\/p>\n\n\n\n <\/p>\n\n\n\n Enginar, %82 su, %12 karbonhidrat, %3 protein ve %3 ya\u011fd\u0131r. 100 graml\u0131k bir referans porsiyonda 74 kalori sa\u011flar, zengin bir folat kayna\u011f\u0131d\u0131r G\u00fcnl\u00fck De\u011ferin %20’si veya daha fazlas\u0131 ve orta d\u00fczeyde bir K vitamini kayna\u011f\u0131d\u0131r (%10-19 DV) (%16) DV), magnezyum, sodyum ve fosfor (%10-12 DV).<\/p>\n\n\n\n Devedikeni fenolik bir bile\u015fiktir. Ana bile\u015fenler \u015funlard\u0131r: Silibinin, Isilibinin vb. Karaci\u011feri koruma, karaci\u011fer fonksiyonunu iyile\u015ftirme, safra salg\u0131s\u0131n\u0131 te\u015fvik etme ve iltihaplanmay\u0131 azaltma i\u015flevine sahiptir. Silymarin karaci\u011feri alkol, kimyasal zehirler, ila\u00e7lar, g\u0131da zehirlenmeleri, \u00e7evre kirlili\u011fi zararlar\u0131ndan koruyabilir; Hepatositlerin rejenerasyonunu ve onar\u0131m\u0131n\u0131 h\u0131zland\u0131r\u0131n.<\/p>\n\n\n\n 1.Silymarin Nedir?<\/p>\n\n\n\n Silymarin, bir t\u00fcr dihidroflavanol bile\u015fi\u011fidir, karaci\u011fer zehirlenmesine direnme, karaci\u011fer h\u00fccrelerini koruma vb. \u0130\u015flevlere sahiptir, safra bo\u015falt\u0131c\u0131 ajan olarak kullan\u0131labilir. Akut, yayg\u0131n hepatit, karaci\u011fer sirozu, metabolizmada toksik karaci\u011fer hasar\u0131, safra ta\u015f\u0131 ve kolanjitin neden oldu\u011fu tekrarlayan a\u011fr\u0131 gibi karaci\u011fer hastal\u0131klar\u0131n\u0131 iyile\u015ftirici etkisi vard\u0131r.<\/p>\n\n\n\n 2.Silymarin Nas\u0131l \u00c7al\u0131\u015f\u0131r?<\/p>\n\n\n\n Silymarin, lipid peroksidasyonunu \u00f6nleyerek ve h\u00fccre zar\u0131 ak\u0131\u015fkanl\u0131\u011f\u0131n\u0131 koruyarak karaci\u011fer h\u00fccre zar\u0131n\u0131 koruyabilir. Ayr\u0131ca, inflamatuar h\u00fccre kaynakl\u0131 hepatosit hasar\u0131n\u0131 azaltmak i\u00e7in n\u00f6trofillerin s\u00fcperoksit anyon sal\u0131n\u0131m\u0131n\u0131 da inhibe eder.<\/p>\n\n\n\n 3. Faydalar ve Kullan\u0131m Alanlar\u0131:<\/p>\n\n\n\n Karaci\u011fer h\u00fccrelerini toksik maddelerden, \u00f6zellikle alkolden ve \u00e7evresel kirleticilerden (b\u00f6cek ila\u00e7lar\u0131, a\u011f\u0131r metaller vb.) korumak; G\u00fc\u00e7l\u00fc bir antioksidan i\u015flevi vard\u0131r, karaci\u011fer h\u00fccrelerini serbest radikal hasar\u0131ndan koruyabilir, E vitamininden \u00e7ok daha etkilidir; Protein sentezini art\u0131r\u0131r, yeni karaci\u011fer h\u00fccrelerinin \u00fcretimini h\u0131zland\u0131r\u0131r veya hasarl\u0131 karaci\u011fer h\u00fccrelerinin kendilerini onarmas\u0131n\u0131 sa\u011flar. Silymarin, anti-radyasyon, anti-aging, damar sertli\u011fini \u00f6nleme ve tedavi etme, cilt ya\u015flanmas\u0131n\u0131 geciktirme ve di\u011fer etkilere sahiptir.<\/p>\n\n\n\n Di\u011fer \u00e7al\u0131\u015fmalar:<\/p>\n\n\n\n Silibinin kronik alkolik karaci\u011fer hastal\u0131\u011f\u0131 olan farelerin lenfositlerinde s\u00fcperoksit dismutaz (SOD) ekspresyonunu art\u0131rabildi\u011fini ve b\u00f6ylece bir antioksidan etkiye sahip oldu\u011funu g\u00f6stermi\u015ftir.<\/p>\n\n\n\n Silibinin reaktif oksijen t\u00fcrleri (ROS) ve malondialdehit (MDA) \u00fcretimini azaltabilece\u011fi de bildirilmi\u015ftir.<\/p>\n\n\n\n Karahindiba y\u00fczy\u0131llard\u0131r m\u00fcshil, mide ilac\u0131, cilt toneri ve artrit, si\u011filler, adet \u00f6ncesi sendromu ve b\u00f6brek ta\u015flar\u0131 i\u00e7in tedavi olarak kullan\u0131lm\u0131\u015ft\u0131r. Ad\u0131, bitkinin yapraklar\u0131ndaki suyu k\u00f6ke ak\u0131tan di\u015f benzeri \u00e7entikler nedeniyle Frans\u0131z dent de aslan\u0131ndan – aslan\u0131n di\u015flerinden – gelir. Avrasya’ya \u00f6zg\u00fc olan karahindiba, g\u0131da ve t\u0131bb\u0131n \u00f6nemli bir bile\u015feni olarak d\u00fcnyan\u0131n geri kalan\u0131na tan\u0131t\u0131ld\u0131. Bitki m\u00fckemmel bir A vitamini, K vitamini ve C vitamini kayna\u011f\u0131d\u0131r; iyi bir lif, kalsiyum ve potasyum kayna\u011f\u0131d\u0131r ve \u0131spanaktan daha fazla protein (fincan ba\u015f\u0131na 1,5 gram) i\u00e7erir. Ye\u015fillikler ayr\u0131ca E vitamini, folat ve di\u011fer B vitaminlerini i\u00e7erir. Bitkinin t\u0131bbi \u00f6zelliklerinin \u00e7o\u011fundan sorumlu olan karahindiba k\u00f6k\u00fc, en ac\u0131 oldu\u011fu haziran, temmuz ve a\u011fustos aylar\u0131nda hasat edilir.<\/p>\n\n\n\n Astaksantin:<\/p>\n\n\n\n Astaksantin, \u00e7e\u015fitli g\u0131dalarda bulunan do\u011fal bir pigment olan bir t\u00fcr karotenoiddir. Bu faydal\u0131 pigment canl\u0131 k\u0131rm\u0131z\u0131-turuncu rengini \u00f6zellikle kril, alg, somon ve \u0131stakoz gibi yiyeceklere verir.<\/p>\n\n\n\n 1. Astaksantin nedir?<\/p>\n\n\n\n Astaksantin, \u00e7e\u015fitli g\u0131dalarda bulunan do\u011fal bir pigment olan bir t\u00fcr karotenoiddir. Bu faydal\u0131 pigment canl\u0131 k\u0131rm\u0131z\u0131-turuncu rengini \u00f6zellikle kril, alg, somon ve \u0131stakoz gibi yiyeceklere verir. Ek formda da bulunabilir ve ayr\u0131ca hayvan ve bal\u0131k yemlerinde g\u0131da boyas\u0131 olarak kullan\u0131lmas\u0131 onaylanm\u0131\u015ft\u0131r.<\/p>\n\n\n\n 2. Astaxanthin’i nas\u0131l elde edebiliriz?<\/p>\n\n\n\n Bir karotenoid olarak, Astaksantin genellikle bir grup ye\u015fil algi kapsayan klorofitte bulunur. Astaksantinin en \u00f6nemli kaynaklar\u0131ndan baz\u0131lar\u0131 aras\u0131nda haematococcus pluvialis ve mayalar phaffia rhodozyma ve xanthophyllomyces dendrorhous bulunur. Mikroalg Haematococcus pluvialis, do\u011fada en y\u00fcksek astaksantin seviyelerini biriktiriyor gibi g\u00f6r\u00fcnmektedir ve \u015fu anda, bir kg kuru biyok\u00fctleden 40 g’dan fazla astaksantinin elde edilebildi\u011fi do\u011fal astaksantin \u00fcretimi i\u00e7in birincil end\u00fcstriyel kaynakt\u0131r.<\/p>\n\n\n\n 3. Astaksantin nas\u0131l \u00e7al\u0131\u015f\u0131r?<\/p>\n\n\n\n Astaksantinin cilt nemini, nem tutmas\u0131n\u0131, elastikiyetini artt\u0131rman\u0131n yan\u0131 s\u0131ra cilt p\u00fcr\u00fczs\u00fczl\u00fc\u011f\u00fcn\u00fc artt\u0131rd\u0131\u011f\u0131, ince \u00e7izgileri ve k\u0131r\u0131\u015f\u0131kl\u0131klar\u0131 azaltt\u0131\u011f\u0131 klinik \u00e7al\u0131\u015fmalarda g\u00f6sterilmi\u015ftir. Astaksantin, cildinizdeki koyu lekeler gibi g\u00fcne\u015fle ili\u015fkili hasarlara kar\u015f\u0131 cildin kendini korumas\u0131na yard\u0131mc\u0131 olan UV engelleme \u00f6zelliklerine sahiptir. Astaksantin, cildinizi ve v\u00fccudunuzu oksidasyon, hasar ve iltihaplanmadan koruyarak birden fazla serbest radikali ayn\u0131 anda n\u00f6tralize edebilir. Astaksantinin kan ak\u0131\u015f\u0131n\u0131 artt\u0131rd\u0131\u011f\u0131, yani cildinizin daha iyi kan dola\u015f\u0131m\u0131na sahip olmas\u0131na yard\u0131mc\u0131 olaca\u011f\u0131 kan\u0131tlanm\u0131\u015ft\u0131r. Artan dola\u015f\u0131m\u0131n, artan h\u00fccre d\u00f6ng\u00fcs\u00fc, g\u00fc\u00e7lendirilmi\u015f elastikiyet ve artan su tutma dahil olmak \u00fczere \u00e7e\u015fitli faydalar\u0131 vard\u0131r.<\/p>\n\n\n\n 4. Faydalar ve Kullan\u0131m Alanlar\u0131:<\/p>\n\n\n\n Beyin Sa\u011fl\u0131\u011f\u0131n\u0131 \u0130yile\u015ftirir Kalbinizi Korur Cildin Par\u0131ldamas\u0131n\u0131 Sa\u011flar Enflamasyonu Kolayla\u015ft\u0131r\u0131r Egzersizinizi Geli\u015ftirir Erkek Do\u011furganl\u0131\u011f\u0131n\u0131 Art\u0131r\u0131r Sa\u011fl\u0131kl\u0131 G\u00f6rmeyi Destekler Kozmetikte Astaksantin \u00dcst tabakan\u0131n (stratum korneum) do\u011fal lipid peroksidasyonu, do\u011fal cilt bariyeri fonksiyonunu azalt\u0131r. Kollajen matrisini par\u00e7alayarak k\u0131r\u0131\u015f\u0131k olu\u015fumuna ve elastikiyet kayb\u0131na neden olabilir. Cilde n\u00fcfuz ederek ve her dermal tabakay\u0131 hasardan koruyan astaksantin, nem kayb\u0131n\u0131 azaltmaya, p\u00fcr\u00fczs\u00fczl\u00fc\u011f\u00fc art\u0131rmaya ve h\u00fccresel yenilenmeyi ortaya \u00e7\u0131karmaya yard\u0131mc\u0131 olur. Ya\u015flanma kar\u015f\u0131t\u0131 Astaksantin, h\u00fccrelerinizi oksidasyondan koruyan bir antioksidand\u0131r, b\u00f6ylece h\u00fccreleriniz daha gen\u00e7 ve hasar g\u00f6rmez. Washington Eyalet \u00dcniversitesi’ndeki ara\u015ft\u0131rmac\u0131lara g\u00f6re, astaksantinin ya\u015flanma s\u00fcrecini yava\u015flatma ve size parlak, temiz bir cilt verme konusunda b\u00fcy\u00fck bir etkisi olabilir. Ba\u015fka bir \u00e7al\u0131\u015fma, yukar\u0131daki ara\u015ft\u0131rman\u0131n bulgular\u0131n\u0131 do\u011frulamaktad\u0131r. D\u00f6rt ay boyunca g\u00fcnde 20 mg astaksantin verilen hayvanlar, beyaz kan h\u00fccrelerinde h\u00fccresel fonksiyonda iyile\u015fme ve ayr\u0131ca daha iyi glutatyon seviyeleri g\u00f6sterdi. Ya\u015fl\u0131l\u0131k Lekelerini Azaltma Bilimsel literat\u00fcre g\u00f6re astaksantin kullan\u0131m\u0131 ciltte olu\u015fan ya\u015fl\u0131l\u0131k lekelerinin azalmas\u0131na neden olabilir. Bir Japon \u00e7al\u0131\u015fmas\u0131nda bilim adamlar\u0131, Astaxanthin kullanan kad\u0131nlar\u0131n 8 haftal\u0131k bir s\u00fcre boyunca ya\u015fl\u0131l\u0131k lekelerinde azalma da dahil olmak \u00fczere g\u00f6zle g\u00f6r\u00fcl\u00fcr cilt iyile\u015ftirmeleri oldu\u011funu buldular. Ba\u015fka bir \u00e7al\u0131\u015fmada erkeklerde benzer sonu\u00e7lar bulundu. K\u0131r\u0131\u015f\u0131kl\u0131k Kar\u015f\u0131t\u0131\/Cilt Esnekli\u011fi Ya\u015fland\u0131k\u00e7a, k\u0131r\u0131\u015f\u0131kl\u0131klar\u0131n say\u0131s\u0131 artar, cilt daha az esnek hale gelir ve cildin ya\u011f \u00fcretimi azal\u0131r ve \u00f6zellikle kuru cilde sahip olanlarda nem i\u00e7eri\u011fi azal\u0131r. Ayn\u0131 Japon \u00e7al\u0131\u015fmalar\u0131, astaksantin alarak kad\u0131nlar\u0131n cildinin k\u0131r\u0131\u015f\u0131kl\u0131klar, elastikiyet ve doku a\u00e7\u0131s\u0131ndan iyile\u015fti\u011fini buldu.<\/p>\n\n\n\n \ud83e\uddea 1. Enginar Ekstresi (Cynara scolymus)<\/p>\n\n\n\n \ud83d\udcc4 Bundy et al., Phytomedicine<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Enginar yaprak ekstrakt\u0131:<\/p>\n\n\n\n Karaci\u011fer enzimlerini d\u00fc\u015f\u00fcrd\u00fc (ALT, AST)<\/p>\n\n\n\n Sindirimi iyile\u015ftirdi<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Hepatoprotektif + sindirim destekleyici<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/15707868\/<\/p>\n\n\n\n \ud83d\udcc4 Holtmann et al.<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Dispepsi hastalar\u0131nda:<\/p>\n\n\n\n Semptomlarda anlaml\u0131 azalma<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Safra ak\u0131\u015f\u0131 ve sindirim destekleyici<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/12559336\/<\/p>\n\n\n\n \ud83e\uddea 2. Devedikeni (Silybum marianum \/ Silymarin)<\/p>\n\n\n\n \ud83d\udcc4 Ferenci et al., Hepatology<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Silymarin:<\/p>\n\n\n\n Karaci\u011fer hasar\u0131n\u0131 azaltt\u0131<\/p>\n\n\n\n Hayatta kal\u0131m\u0131 art\u0131rd\u0131 (siroz hastalar\u0131nda)<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Klinik hepatoprotektif etki<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/8796940\/<\/p>\n\n\n\n \ud83d\udcc4 Loguercio & Festi<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Karaci\u011fer hastal\u0131klar\u0131nda:<\/p>\n\n\n\n ALT\/AST d\u00fc\u015f\u00fc\u015f\u00fc + iyile\u015fme<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Karaci\u011fer fonksiyonunu iyile\u015ftirir<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/16437677\/<\/p>\n\n\n\n \ud83e\uddea 3. Karahindiba (Taraxacum officinale)<\/p>\n\n\n\n \ud83d\udcc4 Choi et al.<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Karahindiba ekstrakt\u0131:<\/p>\n\n\n\n Karaci\u011fer hasar\u0131n\u0131 azaltt\u0131<\/p>\n\n\n\n Antioksidan aktivite \u2191<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Hepatoprotektif + antioksidan<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/19167478\/<\/p>\n\n\n\n \ud83d\udcc4 Ovadje et al.<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Kanser h\u00fccrelerinde:<\/p>\n\n\n\n Apoptozisi tetikledi<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Antikanser potansiyel<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/24603316\/<\/p>\n\n\n\n \ud83e\uddea 4. N-Asetil Karnitin (Acetyl-L-carnitine)<\/p>\n\n\n\n \ud83d\udcc4 Malaguarnera et al.<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Karaci\u011fer hastalar\u0131nda:<\/p>\n\n\n\n Enerji metabolizmas\u0131n\u0131 iyile\u015ftirdi<\/p>\n\n\n\n Karaci\u011fer fonksiyonunu destekledi<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Hepatik enerji deste\u011fi + n\u00f6roprotektif<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/19811302\/<\/p>\n\n\n\n \ud83d\udcc4 Montgomery et al.<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Beyin fonksiyonu:<\/p>\n\n\n\n Kognitif performans artt\u0131<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f N\u00f6roprotektif etki<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/15591013\/<\/p>\n\n\n\n \ud83e\uddea 5. Astaksantin (Astaxanthin)<\/p>\n\n\n\n \ud83d\udcc4 Tominaga et al.<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n 8 hafta kullan\u0131m:<\/p>\n\n\n\n Cilt elastikiyeti \u2191<\/p>\n\n\n\n K\u0131r\u0131\u015f\u0131kl\u0131k \u2193<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Klinik anti-aging etkisi<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/17634699\/<\/p>\n\n\n\n \ud83d\udcc4 Fassett & Coombes<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Kardiyovask\u00fcler sistem:<\/p>\n\n\n\n Damar fonksiyonu iyile\u015fti<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Kalp koruyucu + antioksidan<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/20479936\/<\/p>\n\n\n\n \ud83e\uddea 6. Selenyum (Selenium)<\/p>\n\n\n\n \ud83d\udcc4 Rayman, Lancet<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Selenyum:<\/p>\n\n\n\n Antioksidan enzimleri art\u0131rd\u0131 (glutatyon peroksidaz)<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f H\u00fccresel koruma + ba\u011f\u0131\u015f\u0131kl\u0131k deste\u011fi<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/16310551\/<\/p>\n\n\n\n \ud83d\udcc4 Clark et al.<\/p>\n\n\n\n \ud83d\udc49 Bulgular:<\/p>\n\n\n\n Selenyum takviyesi:<\/p>\n\n\n\n Kanser riskini azaltt\u0131 (\u00f6zellikle prostat)<\/p>\n\n\n\n \ud83d\udccc Sonu\u00e7:<\/p>\n\n\n\n \u27a1\ufe0f Antikanser koruyucu<\/p>\n\n\n\n \ud83d\udd17 https:\/\/pubmed.ncbi.nlm.nih.gov\/15496596\/<\/p>\n","protected":false},"excerpt":{"rendered":" Reishi mantar\u0131 da, di\u011fer t\u0131bbi mantarlar gibi a\u00e7\u0131k havada yeti\u015fen bir mantar t\u00fcr\u00fcd\u00fcr. Bilimsel ad\u0131 Ganoderma lucidum olarak da bilinen Reishi mantar\u0131, yer \u00fcst\u00fcnde, y\u00fczeyde b\u00fcy\u00fcr ve bitkisel ila\u00e7lara, tent\u00fcrlere, \u00e7aylara, toza ve \u00f6zlere d\u00f6n\u00fc\u015ft\u00fcr\u00fclen ba\u011f \u015feritleri (miselyum ad\u0131 verilen) ile birlikte “meyve veren bir v\u00fccut” \u00fcretir. Resihi Mantar\u0131nda Bulunan Polifenoller Nedir? Polifenoller, fenol birimlerinin […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"saved_in_kubio":false,"footnotes":""},"class_list":["post-187","page","type-page","status-publish","hentry"],"kubio_ai_page_context":{"short_desc":"","purpose":"general"},"_links":{"self":[{"href":"https:\/\/www.pharmemin.com\/index.php\/wp-json\/wp\/v2\/pages\/187","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pharmemin.com\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.pharmemin.com\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.pharmemin.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pharmemin.com\/index.php\/wp-json\/wp\/v2\/comments?post=187"}],"version-history":[{"count":1,"href":"https:\/\/www.pharmemin.com\/index.php\/wp-json\/wp\/v2\/pages\/187\/revisions"}],"predecessor-version":[{"id":193,"href":"https:\/\/www.pharmemin.com\/index.php\/wp-json\/wp\/v2\/pages\/187\/revisions\/193"}],"wp:attachment":[{"href":"https:\/\/www.pharmemin.com\/index.php\/wp-json\/wp\/v2\/media?parent=187"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}![\"\"](\"https:\/\/www.pharmemin.com\/wp-content\/uploads\/2026\/03\/h47-2-819x1024.png\")
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